Greta Ehlers and Dr. Stefanie Hofer: Research & Patient Centricity

Greta Ehlers and Dr. Stefanie Hofer: Research & Patient Centricity

Greta Ehlers and Dr. Stefanie Hofer: Research & Patient Centricity

Recently, Greta Ehlers from our Business Development Team and Dr. Stefanie Hofer from our Clinical Research Team joined Tinotenda Dzikiti on his podcast “The Diabetic Mogul”, talking about research and patient centricity at DCB.

Research and Patient Centricity at DCB

In this podcast episode, Greta Ehlers and Dr. Stefanie Hofer from the DCB team give insights into their own lives with type 1 diabetes as well as their professional backgrounds in the diabetes field. In doing so, they specifically delve into the research we do at DCB and our strong commitment to patient centricity.

You can listen to the podcast below:

    Research & Patient Centricity are Essential

    About “The Diabetic Mogul” podcast

    “The Diabetic Mogul Podcast”, is hosted by Tinotenda Dzikiti (Certified Diabetes Educator) and Konstantina Taki (Medical Doctor) and who are Patient Advocates. Both Tino & Konna are co-hosting a series of podcast episodes, as they envision to inspire, empower, encourage and educate the community to prevent/manage diabetes. Their hope is that “everyone could get involved, get engaged, and come up together to create the change that this World needs.”

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      DCB on ADA TV: Driving Diabetes Technology Innovation

      DCB on ADA TV: Driving Diabetes Technology Innovation

      DCB on ADA TV: Driving Diabetes Technology Innovation

      As the American Diabetes Association’s 83rd Scientific Session are being held in San Diego, CA, from 23-26 June, a short movie about DCB’s mission of driving diabetes technology innovation will be broadcast across the convention center as well as conference hotels and shuttle busses.

      Learn more about DCB’s mission on ADA TV

      During the American Diabetes Association’s 83rd Scientific Session, a short movie about DCB’s mission will be broadcast across the convention center and associated areas. The movie produced for ADA TV features employees as well as associated research teams of DCB and brings the mission of driving diabetes technology innovation to screens all over.

      Other than on-site at the American Diabetes Association’s 83rd Scientific Sessions, it is also available to watch online:

      Driving Diabetes Technology Innovation - Diabetes Center Berne

      DCB thanks the American Diabetes Association and the production company WebsEdge Medicine for this great collaboration and for giving the DCB mission a stage at the ADA congress.

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      Start-up funding in diabetes technology: DCB Innovation Challenge enters new round 

      Start-up funding in diabetes technology: DCB Innovation Challenge enters new round 

      Start-up funding in diabetes technology: DCB Innovation Challenge enters new round 

      For the third time, the Diabetes Center Berne is launching the Open Innovation Challenge with the aim of specifically promoting innovative projects in the field of diabetes management on Swiss and international level. Participating start-ups benefit from professional expert feedback, and the three best projects in each of the categories Diabetes Devices and Digital Diabetes receive access to a bootcamp. The finalists will receive prize money of up to USD 100,000 and further support from the DCB. The DCB Innovation Challenge is the world’s largest diabetes technology award with international appeal.

      More than 537 million people worldwide live with diabetes, which means a constant challenge in everyday life for those affected. Technological innovations make an important contribution to making it easier to deal with diabetes – whether it is measuring glucose levels or now even planning the amount of insulin needed via an app. But despite these enormous advances in diabetes technology, there is still a great, unmet need for innovative technical solutions. These should help to ease the challenge for users in everyday life and improve the lives of people with diabetes in the long term.

      Two categories: Diabetes Devicesand “Digital Diabetes

      In the last edition of the Open Innovation Challenge 2022, start-ups GO-Pen from Denmark and Una Health from Germany were named winners in their respective categories. GO-Pen is developing a cost-effective, reliable and sustainable insulin pen, while Una Health enables people with type 2 diabetes to understand the causes of their condition and make simple and targeted changes to improve their health.

      In the new edition of the Innovation Challenge 2023, there are again two categories: on the one hand for medical devices, such as insulin pens, insulin pumps or sensors for continuous glucose measurement. The other is for digital solutions such as apps for diabetes management, which can include monitoring glucose levels, nutrition and exchanging information with other people with diabetes. For the category “Diabetes Devices”, the kick-off will be at the beginning of May 2023, “Digital Diabetes” will start at the beginning of June 2023. After a first round and feedback from the expert jury, the top 20 will enter a mentoring programme. The three best projects will be invited to a bootcamp individually tailored to them. On 9 November 2023, the winning project will be selected by an international jury and rewarded with 100,000 USD including in-kind support such as coaching. Second and third place will each receive USD 20,000 including further support. The DCB Open Innovation Challenge is thus the world’s largest diabetes technology award with international appeal. Start-ups, medical and research professionals, but also individuals can apply.

      Closing gaps with a translational approach

      “At the DCB, we want to close the gaps between ideas, clinical trials and start-ups through innovation.  We are also pursuing this goal with the DCB Open Innovation Challenge, which connects start-ups, mentors, corporates and the international diabetes community. In this way, we can help real innovative ideas in diabetes management to achieve a breakthrough. Not only with funding, but also with targeted support from our partner network,” says Dr Maren Schinz, responsible for the DCB Open Innovation Challenge.

      Do you have an innovative idea to facilitate change diabetes management forever? Want to see how your idea becomes reality? Do you have valuable insights to help co-create the diabetes technology of tomorrow? Do you have feedback to share with others in the community? Then sign up to our Innovation Platform and participate in the DCB Open Innovation Challenge 2023! You can find more information here.

      Media release

      PDF, 437.68 KB

      Innovation Challenge 2023

      Information sheet

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      José Garcia-Tirado takes up position as professor specialising in technology-assisted precision medicine

      José Garcia-Tirado takes up position as professor specialising in technology-assisted precision medicine

      José Garcia-Tirado takes up position as professor specialising in technology-assisted precision medicine

      The newly created assistant professorship with tenure track is the second of a total of three professorships in the field of “Diabetes Technology and Artificial Pancreas” jointly created by the University of Bern, the Inselgruppe and the Diabetes Center Berne (DCB).

      Focus on fully automated insulin delivery

      Before taking up his new position, Garcia-Tirado was an assistant professor at the University of Virginia. His research focuses on fully automated insulin delivery, also called artificial pancreas or closed-loop system, as well as conducting corresponding clinical trials.

      “I am very excited to contribute to the field of diabetes technology as part of the joint venture between the University of Bern Clinic for Diabetology, Endocrinology, Nutritional Medicine and Metabolism (UDEM) and the Diabetes Center Berne (DCB) by developing new intelligent algo- rithms for automated insulin delivery and decision support systems for people with diabetes,”says Garcia-Tirado.

      Derek Brandt, CEO of the DCB adds: “In addition to Lilian Witthauer, professor in the field of sensor technology, we have taken a second and important step with Professor Garcia-Tirado for the topic of closed-loop systems. This enables us to play an international pioneering role in the field of translational diabetes technology research. We are doing everything we can to further improve daily life for people with diabetes“.

      José Garcia-Tirado

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      DCB joins the OPEN project: evidence on the clinical and person​-​reported outcomes of open​-​source automated insulin delivery (AID) system users

      DCB joins the OPEN project: evidence on the clinical and person​-​reported outcomes of open​-​source automated insulin delivery (AID) system users

      DCB joins the OPEN project: evidence on the clinical and person​-​reported outcomes of open​-​source automated insulin delivery (AID) system users

      Bern, September 14, 2022 – DCB has become a new consortium member of the OPEN project – a patient-led research project gathering real-world evidence on the clinical and quality of life outcomes of open-source automated insulin delivery (AID) system users to better understand their impact on the lives of people with diabetes.

      Today, modern therapy methods such as sensors for continuous glucose monitoring and insulin pumps are available for people with diabetes in selected countries. Nevertheless, only a small proportion of people with diabetes reach the long-term outcome parameters recommended by therapeutic guidelines of an hemoglobin A1c value <7.0%. In closed-loop systems, also known as “artificial pancreas” or “automated insulin delivery” (AID) systems, a control algorithm continuously and automatically adjusts insulin dosing of an insulin pump according to an individual’s predicted glucose levels and insulin needs.

      However, research, commercial development and regulatory approval of such technologies are resource heavy, time consuming and complex. Under the mantra #WeAreNotWaiting, tech-savvy people with diabetes have therefore started building their own AID systems. Based on the principle of “paying it forward”, instructions and code needed to build and maintain these systems as well as community peer-support are freely available on open-source platforms online.

      Photo: Researchers of the OPEN project

      The team found that people who are using these systems not only experienced significant improvements of their physical, but also tremendous improvements in the quality of life and sleep. OPEN has moreover established an international consensus statement of 48 healthcare professionals and legal experts that provides theoretical background and practical guidance for healthcare professionals who wish to support individuals using open-source AID, which was part of the “100 years of insulin” special issue of The Lancet.

      “Our research is enabling healthcare providers, academia, device manufacturers and regulators to understand open-source AID systems, that people using them feel safe, and experience a variety of positive changes related to their diabetes management, mental and physical health.” – says Dr. Shane O’Donnell, research scientist at University College Dublin and project coordinator of OPEN.

      An international consortium of well-established research and patient advocacy organisations

      With DCB joining the OPEN project in June 2022, the consortium now consists of 11 members, including the University College Dublin, Charité – Universitätsmedizin Berlin, Dedoc Labs GmbH, the Australian Centre for Behavioural Research in Diabetes, the University of Copenhagen, Stanford University, and King’s College London.

      Visual: The OPEN consortium (Status: September 2022)

      Dr. Maren Schinz, Innovation Manager at DCB says: ”DCB is a great fit as a consortium member, and we are very proud to contribute to this mutual exchange of knowledge. With OPEN being a flagship project of community involvement, it perfectly matches what we want to achieve at DCB: identifying unmet needs and translating science into real solutions to ultimately improve the lives of people with diabetes.”

      About OPEN

      The OPEN project consists of an international and cross-cutting and patient-led consortium that aims to build an evidence base around the impact of open-source AID systems on people with diabetes across several regions of the world.

      Media contacts

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      Collaboration with SmartStart Health to unlock life​-​changing benefits of CGM in diabetes

      Collaboration with SmartStart Health to unlock life​-​changing benefits of CGM in diabetes

      Collaboration with SmartStart Health to unlock life​-​changing benefits of CGM in diabetes

      Berne and London, 11 April 2022: Today DCB and SmartStart Health announced their collaboration to develop and validate a world-first patient education mobile app to increase knowledge and improve outcomes among people with diabetes using continuous glucose monitoring (CGM).

      • DCB Innovation, a division of the Swiss Diabetes Center Berne (DCB), has partnered with UK startup SmartStart Health to launch SmartStart CGM, the first digital support app for people with diabetes using continuous glucose monitoring (CGM) technology
      • CGM is currently used by c.40% of Americans with type 1 diabetes; worldwide, nearly 50% of people with type 2 diabetes on frequent insulin injections are expected to adopt CGM by 2030[i]
      • Scalable education provided by SmartStart CGM will help healthcare professionals support more patients to benefit from CGM

      CGM technology constantly tracks glucose levels and can alert users when they are too high or too low. Despite proven health benefits, starting on CGM can be complex and overwhelming for people with diabetes. As many as 27% of CGM users discontinue use in the first year and up to 30% use the technology too inconsistently to benefit from it.[ii] Patients with more education regarding CGM use have better outcomes[iii] and more research is needed to create high-quality, evidence-based training and support.[iv] CGM use is expanding rapidly, creating the need for a scalable solution.

      Melissa Holloway, CEO and Founder of SmartStart Health

      SmartStart Health is rising to the challenge of CGM-specific patient education with SmartStart CGM, a user-friendly smartphone app. Supported by DCB, diabetes centres in the US and Switzerland will evaluate the new scalable solution in a proof-of-concept study. The partnership aims to analyse the results in Q3 2022 and publish by mid-2023.

      “CGMs can make everyday life easier for people living with diabetes – provided they receive a proper introduction to the technology as well as ongoing support. At DCB, we are truly convinced that SmartStart Health will contribute significantly to achieving this,” said Derek Brandt, CEO of DCB.

      The SmartStart CGM app is designed to inform and empower users with interactive micro-learning based on real-world scenarios that reflect the reality of living with diabetes. A telehealth portal for healthcare professionals will enable clinicians to assess patient engagement with the programme.

      Dr. Thomas Grace, a diabetes specialist from Ohio, US, who will use the new CGM education app in his practice as part of the proof-of-concept study, said:

      “Starting on CGM can bring a real learning curve for patients as well as a time commitment for my team. I’m excited to use SmartStart CGM to support our patients in using CGM and optimise our interactions.”

      SmartStart Health Founder and CEO Melissa Holloway said:

      “As a long-term user of CGM providing peer support to fellow CGM users every day, I am passionate about supporting people with diabetes to get the best out of this life-changing technology. The goal for SmartStart CGM is to unlock the benefits of CGM for more people.”

      For more information on SmartStart CGM, visit the SmartStart Health website at www.smartstart.health and subscribe to updates.

      [i] https://www.healthcaredive.com/news/abbott-dexcom-diabetes-tech-type-2-jefferies/608157

      [ii] Yu S et al. Diabetes Technol Ther 2018;20(6):420–427. https://doi.org/10.1089/dia.2017.0435

      [iii] American Diabetes Association Professional Practice Committee; 7. Diabetes Technology: Standards of Medical Care in Diabetes—2022Diabetes Care 1 January 2022; 45 (Supplement_1): S97–S112. https://doi.org/10.2337/dc22-S00

      [iv] Heinemann L, Klonoff DC. J Diabetes Sci Technol 2020 (6):983-986. https://doi.org/10.1177/1932296819895083

      About SmartStart Health

      As an advocate for access to diabetes technology, Melissa Holloway identified the need for validated, scalable continuous glucose monitoring (CGM) user education through thousands of peer interactions with other people living with type 1 diabetes. With nearly 20 years of diabetes industry experience, Melissa founded SmartStart Health after participating in the 2021 DCB Open Innovation Challenge.

      SmartStart Health is developing SmartStart CGM, an app-based education program to support patient onboarding and diabetes self-management with CGM. The app provides interactive mobile learning modules to empower people living with diabetes to learn about CGM and offers a telehealth portal to help healthcare teams tailor clinical care for CGM users.

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