SPN-005 – Pilot study on painless glucose monitoring

Project description:
For people with Type 1 Diabetes, multiple daily finger pricks to check blood sugar levels are common practice. This project evaluates a novel non-invasive technology developed by Liom Health AG, which uses light and artificial intelligence to measure glucose levels through the skin in real time — without finger pricks.

Methodology:
In a pilot study with 21 participants, a carefully controlled sequence of blood glucose fluctuations was induced to assess the device’s accuracy. Conventional blood glucose measurements and continuous glucose monitoring (CGM) systems were used in parallel.

Results:
The device readings showed good agreement with established methods, with most measurements falling within clinically acceptable ranges. No health risks or technical issues were observed.

Conclusion:
The study indicates that painless glucose monitoring without fingersticks or CGM could be feasible. However, further research is required to improve accuracy and reliability before market readiness.

Partner: Liom Health AG (formerly Spiden AG), University Clinic for Diabetology, Endocrinology, Nutritional Medicine & Metabolism (UDEM)
Category: Clinical pilot study
Year: 2023-2024