{"id":10264,"date":"2025-01-24T14:47:37","date_gmt":"2025-01-24T14:47:37","guid":{"rendered":"https:\/\/www.dcberne.com\/?post_type=project&#038;p=10264"},"modified":"2025-01-24T14:56:32","modified_gmt":"2025-01-24T14:56:32","slug":"obesogenic-microbiota-project","status":"publish","type":"project","link":"https:\/\/www.dcberne.com\/en\/project\/obesogenic-microbiota-project\/","title":{"rendered":"Obesogenic microbiota Project"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;1px||0px||false|false&#8221; custom_margin_tablet=&#8221;1px||0px||false|false&#8221; custom_margin_phone=&#8221;3px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; border_width_top=&#8221;0.5px&#8221; border_color_top=&#8221;#505358&#8243; border_width_bottom=&#8221;0.5px&#8221; border_color_bottom=&#8221;#505358&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.19.4&#8243; 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global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_post_title title=&#8221;off&#8221; author=&#8221;off&#8221; date=&#8221;off&#8221; comments=&#8221;off&#8221; featured_image=&#8221;off&#8221; module_id=&#8221;meta-new&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;Avant Regular||||||||&#8221; title_text_color=&#8221;#000000&#8243; title_font_size=&#8221;64px&#8221; title_line_height=&#8221;70px&#8221; meta_font=&#8221;Calibri Regular||||||||&#8221; meta_text_color=&#8221;RGBA(255,255,255,0)&#8221; meta_font_size=&#8221;10px&#8221; meta_line_height=&#8221;16px&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||20px||false|false&#8221; custom_css_post_meta=&#8221;text-transform: uppercase;&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_post_title][et_pb_post_title author=&#8221;off&#8221; date_format=&#8221;j \u00b7 M \u00b7 Y&#8221; comments=&#8221;off&#8221; featured_image=&#8221;off&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;Avant Regular||||||||&#8221; title_text_color=&#8221;#000000&#8243; title_font_size=&#8221;64px&#8221; title_line_height=&#8221;70px&#8221; meta_font=&#8221;Avant Regular||||||||&#8221; meta_text_color=&#8221;#000000&#8243; meta_font_size=&#8221;14px&#8221; meta_line_height=&#8221;24px&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||16px||false|false&#8221; title_font_size_tablet=&#8221;&#8221; title_font_size_phone=&#8221;42px&#8221; title_font_size_last_edited=&#8221;on|phone&#8221; title_line_height_tablet=&#8221;&#8221; title_line_height_phone=&#8221;48px&#8221; title_line_height_last_edited=&#8221;on|phone&#8221; custom_css_post_meta=&#8221;text-transform: uppercase;&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_post_title][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Avant Regular||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;20px&#8221; text_line_height=&#8221;24px&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span>Exploring the connection: obesity, gut microbiome, and metabolic health<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; module_id=&#8221;post-content&#8221; _builder_version=&#8221;4.27.3&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;589px&#8221; custom_margin=&#8221;30px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Avant Regular||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;30px&#8221; text_line_height=&#8221;36px&#8221; link_font=&#8221;||||on|||#89BBE5|&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||16px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span>Cause and effect relationship between obesity and gut microbiome <\/span><\/p>\n<p>[\/et_pb_text][et_pb_text ul_item_indent=&#8221;20px&#8221; ol_item_indent=&#8221;20px&#8221; module_id=&#8221;post-body&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Calibri Regular||||||||&#8221; text_text_color=&#8221;#505358&#8243; text_font_size=&#8221;18px&#8221; text_line_height=&#8221;24px&#8221; link_font=&#8221;||||on|||#89BBE5|&#8221; link_text_color=&#8221;#89BBE5&#8243; min_height=&#8221;67px&#8221; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;0px||80px||false|false&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Global rises in metabolic diseases such as obesity and diabetes pose severe medical and socio-economic threats, influenced by a variety of both genetic and environmental factors. Chronic inflammation links these diseases, suggesting an impact on the immune system. The human intestinal flora, especially the metabolic products it produces, appear to play a role in the development of obesity and diabetes.<\/p>\n<p>To understand the underlying mechanisms, our project utilizes innovative methods (gnotobiotics, metagenomics and metabolomics) to explore the relationship between gut flora, metabolism and immune function. By unraveling these relationships, we aim to lay the foundation for innovative strategies to prevent and treat these diseases.<\/p>\n<p><b>Project team:<\/b><span style=\"font-weight: 400;\"> Melanie Scalise, June Stone<br \/><strong>Funding:\u00a0<\/strong>SNSF<\/span><a href=\"https:\/\/qumea.com\/\"><\/a><span style=\"font-weight: 400;\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.dcberne.com\/wp-content\/uploads\/2025\/01\/PastedGraphic-3.png&#8221; title_text=&#8221;PastedGraphic-3&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; 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custom_padding=&#8221;0px||40px||false|false&#8221; custom_padding_tablet=&#8221;0px||40px||false|false&#8221; custom_padding_phone=&#8221;||16px||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>More recent projects<\/p>\n<p>[\/et_pb_text][et_pb_blog fullwidth=&#8221;off&#8221; post_type=&#8221;project&#8221; posts_number=&#8221;3&#8243; meta_date=&#8221;j \u00b7 M \u00b7 Y&#8221; excerpt_length=&#8221;120&#8243; show_author=&#8221;off&#8221; show_pagination=&#8221;off&#8221; masonry_tile_background_color=&#8221;RGBA(255,255,255,0)&#8221; module_class=&#8221;dcb-news&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;Avant Regular||||||||&#8221; header_text_color=&#8221;#000000&#8243; header_font_size=&#8221;20px&#8221; header_line_height=&#8221;24px&#8221; body_font=&#8221;Calibri Regular||||||||&#8221; body_text_color=&#8221;#505358&#8243; body_font_size=&#8221;16px&#8221; 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custom_css_title_phone=&#8221;margin-bottom: 16px;&#8221; custom_css_content_last_edited=&#8221;on|phone&#8221; custom_css_content_phone=&#8221;margin-bottom: 24px;&#8221; custom_css_post_meta_last_edited=&#8221;on|phone&#8221; custom_css_post_meta_tablet=&#8221;text-transform: uppercase;&#8221; custom_css_post_meta_phone=&#8221;text-transform: uppercase;&#8221;][\/et_pb_blog][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;252.2px&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;32px||32px||false|false&#8221; border_width_top=&#8221;0.5px&#8221; border_color_top=&#8221;#505358&#8243; global_module=&#8221;283&#8243; saved_tabs=&#8221;all&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; 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Chronic inflammation links these diseases, suggesting an impact on the immune system. [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":10272,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"give_campaign_id":0,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[62,60,59,47],"project_tag":[],"class_list":["post-10264","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-commitment-clinical-studies","project_category-nutrition-metabolism","project_category-commitment-research-projects","project_category-commitment-technology-projects"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Obesogenic microbiota Project - Diabetes Center Berne<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.dcberne.com\/en\/project\/obesogenic-microbiota-project\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Obesogenic microbiota Project - Diabetes Center Berne\" \/>\n<meta property=\"og:description\" content=\"Exploring the connection: obesity, gut microbiome, and metabolic healthCause and effect relationship between obesity and gut microbiome Global rises in metabolic diseases such as obesity and diabetes pose severe medical and socio-economic threats, influenced by a variety of both genetic and environmental factors. Chronic inflammation links these diseases, suggesting an impact on the immune system. 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