{"id":2007,"date":"2022-09-14T15:01:34","date_gmt":"2022-09-14T15:01:34","guid":{"rendered":"https:\/\/www.dcberne.com\/?p=2007"},"modified":"2023-02-01T08:18:00","modified_gmt":"2023-02-01T08:18:00","slug":"dcb-joins-the-open-project-evidence-on-the-clinical-and-person-reported-outcomes-of-open-source-automated-insulin-delivery-aid-system-users","status":"publish","type":"post","link":"https:\/\/www.dcberne.com\/en\/dcb-joins-the-open-project-evidence-on-the-clinical-and-person-reported-outcomes-of-open-source-automated-insulin-delivery-aid-system-users\/","title":{"rendered":"DCB joins the OPEN project: evidence on the clinical and person\u200b-\u200breported outcomes of open\u200b-\u200bsource automated insulin delivery (AID) system users"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;1px||0px||false|false&#8221; custom_margin_tablet=&#8221;1px||0px||false|false&#8221; 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custom_button=&#8221;on&#8221; button_text_size=&#8221;12px&#8221; button_text_color=&#8221;#000000&#8243; button_bg_color=&#8221;#FFFFFF&#8221; button_border_width=&#8221;0px&#8221; button_font=&#8221;Avant Regular||||||||&#8221; button_icon=&#8221;&#x23;||divi||400&#8243; button_icon_color=&#8221;#89bbe5&#8243; button_icon_placement=&#8221;left&#8221; button_on_hover=&#8221;off&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221; button_text_color__hover_enabled=&#8221;on|hover&#8221; button_text_color__hover=&#8221;#89bbe5&#8243; button_bg_color__hover_enabled=&#8221;on|desktop&#8221; button_bg_color__hover=&#8221;#FFFFFF&#8221; button_bg_enable_color__hover=&#8221;on&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;80px||80px||false|false&#8221; custom_padding_tablet=&#8221;80px||80px||false|false&#8221; custom_padding_phone=&#8221;40px||80px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_post_title title=&#8221;off&#8221; author=&#8221;off&#8221; date=&#8221;off&#8221; comments=&#8221;off&#8221; featured_image=&#8221;off&#8221; module_id=&#8221;meta-new&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;Avant Regular||||||||&#8221; title_text_color=&#8221;#000000&#8243; title_font_size=&#8221;64px&#8221; title_line_height=&#8221;70px&#8221; meta_font=&#8221;Calibri Regular||||||||&#8221; meta_text_color=&#8221;RGBA(255,255,255,0)&#8221; meta_font_size=&#8221;10px&#8221; meta_line_height=&#8221;16px&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||20px||false|false&#8221; custom_css_post_meta=&#8221;text-transform: uppercase;&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_post_title][et_pb_post_title author=&#8221;off&#8221; date_format=&#8221;j \u00b7 M \u00b7 Y&#8221; categories=&#8221;off&#8221; comments=&#8221;off&#8221; featured_image=&#8221;off&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;Avant Regular||||||||&#8221; title_text_color=&#8221;#000000&#8243; title_font_size=&#8221;64px&#8221; title_line_height=&#8221;70px&#8221; meta_font=&#8221;Avant Regular||||||||&#8221; meta_text_color=&#8221;#000000&#8243; meta_font_size=&#8221;14px&#8221; meta_line_height=&#8221;24px&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||16px||false|false&#8221; title_font_size_tablet=&#8221;64px&#8221; title_font_size_phone=&#8221;42px&#8221; title_font_size_last_edited=&#8221;on|phone&#8221; title_line_height_tablet=&#8221;70px&#8221; title_line_height_phone=&#8221;48px&#8221; title_line_height_last_edited=&#8221;on|phone&#8221; custom_css_post_meta=&#8221;text-transform: uppercase;&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_post_title][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Avant Regular||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;20px&#8221; text_line_height=&#8221;24px&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Bern, September 14, 2022 \u2013 DCB has become a new consortium member of the OPEN project \u2013 a patient-led research project gathering real-world evidence on the clinical and quality of life outcomes of open-source automated insulin delivery (AID) system users to better understand their impact on the lives of people with diabetes.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;3_5,2_5&#8243; module_id=&#8221;post-content&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text ul_item_indent=&#8221;20px&#8221; ol_item_indent=&#8221;20px&#8221; module_id=&#8221;post-body&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Calibri Regular||||||||&#8221; text_text_color=&#8221;#505358&#8243; text_font_size=&#8221;18px&#8221; text_line_height=&#8221;24px&#8221; link_font=&#8221;||||on|||#89BBE5|&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;0px||80px||false|false&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Today, modern therapy methods such as sensors for continuous glucose monitoring and insulin pumps are available for people with diabetes in selected countries. Nevertheless, only a small proportion of people with diabetes reach the long-term outcome parameters recommended by therapeutic guidelines of an hemoglobin A1c value &lt;7.0%. In closed-loop systems, also known as \u201cartificial pancreas\u201d or \u201cautomated insulin delivery\u201d (AID) systems, a control algorithm continuously and automatically adjusts insulin dosing of an insulin pump according to an individual\u2019s predicted glucose levels and insulin needs.<\/p>\n<p>However, research, commercial development and regulatory approval of such technologies are resource heavy, time consuming and complex. Under the mantra #WeAreNotWaiting, tech-savvy people with diabetes have therefore started building their own AID systems. Based on the principle of \u201cpaying it forward\u201d, instructions and code needed to build and maintain these systems as well as community peer-support are freely available on open-source platforms online.<\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.dcberne.com\/wp-content\/uploads\/2022\/12\/OPEN_Team-1024&#215;683-1.jpg&#8221; title_text=&#8221;OPEN_Team-1024&#215;683&#8243; show_bottom_space=&#8221;off&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||16px||false|false&#8221; custom_padding_tablet=&#8221;0px||16px||false|false&#8221; custom_padding_phone=&#8221;||8px||false|false&#8221; custom_padding_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Calibri Regular||||||||&#8221; text_text_color=&#8221;#505358&#8243; text_line_height=&#8221;20px&#8221; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Photo: Researchers of the OPEN project<\/p>\n<p>[\/et_pb_text][et_pb_text ul_item_indent=&#8221;20px&#8221; ol_item_indent=&#8221;20px&#8221; module_id=&#8221;post-body&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Calibri Regular||||||||&#8221; text_text_color=&#8221;#505358&#8243; text_font_size=&#8221;18px&#8221; text_line_height=&#8221;24px&#8221; link_font=&#8221;||||on|||#89BBE5|&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;0px||80px||false|false&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span>The team found that people who are using these systems not only experienced significant improvements of their physical, but also tremendous improvements in the quality of life and sleep. OPEN has moreover established an international consensus statement of 48 healthcare professionals and legal experts that provides theoretical background and practical guidance for healthcare professionals who wish to support individuals using open-source AID, which was part of the \u201c100 years of insulin\u201d special issue of\u00a0<\/span><em>The Lancet<\/em><span>.<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Avant Regular||on||||||&#8221; text_text_color=&#8221;#505358&#8243; text_font_size=&#8221;30px&#8221; text_line_height=&#8221;40px&#8221; link_text_color=&#8221;#89BBE5&#8243; background_image=&#8221;https:\/\/www.dcberne.com\/wp-content\/uploads\/2022\/12\/Ellipse-24.png&#8221; background_size=&#8221;contain&#8221; background_position=&#8221;center_left&#8221; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;0px||80px||false|false&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;40px||40px||false|false&#8221; custom_padding_tablet=&#8221;40px||40px||false|false&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; text_font_size_tablet=&#8221;30px&#8221; text_font_size_phone=&#8221;24px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; text_line_height_tablet=&#8221;40px&#8221; text_line_height_phone=&#8221;32px&#8221; text_line_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; custom_margin__hover_enabled=&#8221;off|hover&#8221; custom_margin__hover=&#8221;||48px||false|false&#8221;]<\/p>\n<p><span>\u201cOur research is enabling healthcare providers, academia, device manufacturers and regulators to understand open-source AID systems, that people using them feel safe, and experience a variety of positive changes related to their diabetes management, mental and physical health.\u201d \u2013 says Dr. Shane O\u2019Donnell, research scientist at University College Dublin and project coordinator of OPEN.<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Avant Regular||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;30px&#8221; text_line_height=&#8221;36px&#8221; link_font=&#8221;||||on|||#89BBE5|&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||16px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>An international consortium of well-established research and patient advocacy organisations<\/p>\n<p>[\/et_pb_text][et_pb_text ul_item_indent=&#8221;20px&#8221; ol_item_indent=&#8221;20px&#8221; module_id=&#8221;post-body&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Calibri Regular||||||||&#8221; text_text_color=&#8221;#505358&#8243; text_font_size=&#8221;18px&#8221; text_line_height=&#8221;24px&#8221; link_font=&#8221;||||on|||#89BBE5|&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;0px||80px||false|false&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>With DCB joining the OPEN project in June 2022, the consortium now consists of 11 members, including the University College Dublin, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Dedoc Labs GmbH, the Australian Centre for Behavioural Research in Diabetes, the University of Copenhagen, Stanford University, and King\u2019s College London.<\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.dcberne.com\/wp-content\/uploads\/2022\/12\/OPEN_Konsortium-1024&#215;791-1.png&#8221; title_text=&#8221;OPEN_Konsortium-1024&#215;791&#8243; show_bottom_space=&#8221;off&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||16px||false|false&#8221; custom_padding_tablet=&#8221;0px||16px||false|false&#8221; custom_padding_phone=&#8221;||8px||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Calibri Regular||||||||&#8221; text_text_color=&#8221;#505358&#8243; text_line_height=&#8221;20px&#8221; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Visual: The OPEN consortium (Status: September 2022)<\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Avant Regular||on||||||&#8221; text_text_color=&#8221;#505358&#8243; text_font_size=&#8221;30px&#8221; text_line_height=&#8221;40px&#8221; link_text_color=&#8221;#89BBE5&#8243; background_image=&#8221;https:\/\/www.dcberne.com\/wp-content\/uploads\/2022\/12\/Ellipse-24.png&#8221; background_size=&#8221;contain&#8221; background_position=&#8221;center_left&#8221; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;40px||40px||false|false&#8221; custom_padding_tablet=&#8221;40px||40px||false|false&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;24px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; text_line_height_tablet=&#8221;&#8221; text_line_height_phone=&#8221;32px&#8221; text_line_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; custom_margin__hover_enabled=&#8221;off|hover&#8221; custom_margin__hover=&#8221;||48px||false|false&#8221;]<\/p>\n<p><span>Dr. Maren Schinz, Innovation Manager at DCB says: \u201dDCB is a great fit as a consortium member, and we are very proud to contribute to this mutual exchange of knowledge. With OPEN being a flagship project of community involvement, it perfectly matches what we want to achieve at DCB: identifying unmet needs and translating science into real solutions to ultimately improve the lives of people with diabetes.\u201d<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Avant Regular||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;30px&#8221; text_line_height=&#8221;36px&#8221; link_font=&#8221;||||on|||#89BBE5|&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||16px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>About OPEN<\/p>\n<p>[\/et_pb_text][et_pb_text ul_item_indent=&#8221;20px&#8221; ol_item_indent=&#8221;20px&#8221; module_id=&#8221;post-body&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;Calibri Regular||||||||&#8221; text_text_color=&#8221;#505358&#8243; text_font_size=&#8221;18px&#8221; text_line_height=&#8221;24px&#8221; link_font=&#8221;||||on|||#89BBE5|&#8221; link_text_color=&#8221;#89BBE5&#8243; custom_margin=&#8221;0px||80px||false|false&#8221; custom_margin_tablet=&#8221;0px||80px||false|false&#8221; custom_margin_phone=&#8221;||48px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span>The OPEN project consists of an international and cross-cutting and patient-led consortium that aims to build an evidence base around the impact of open-source AID systems on people with diabetes across several regions of the world.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||64px|false|false&#8221; 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