{"id":9869,"date":"2024-12-19T14:46:10","date_gmt":"2024-12-19T14:46:10","guid":{"rendered":"https:\/\/www.dcberne.com\/?post_type=project&#038;p=9869"},"modified":"2025-01-24T14:54:32","modified_gmt":"2025-01-24T14:54:32","slug":"hypoxanthin-projekt","status":"publish","type":"project","link":"https:\/\/www.dcberne.com\/de\/project\/hypoxanthin-projekt\/","title":{"rendered":"Bakterielle Metaboliten modulieren die Immunfunktion"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8220;1&#8243; _builder_version=&#8220;4.19.4&#8243; _module_preset=&#8220;default&#8220; custom_margin=&#8220;1px||0px||false|false&#8220; custom_margin_tablet=&#8220;1px||0px||false|false&#8220; custom_margin_phone=&#8220;3px||||false|false&#8220; custom_margin_last_edited=&#8220;on|phone&#8220; custom_padding=&#8220;0px||0px||false|false&#8220; border_width_top=&#8220;0.5px&#8220; border_color_top=&#8220;#505358&#8243; border_width_bottom=&#8220;0.5px&#8220; border_color_bottom=&#8220;#505358&#8243; global_colors_info=&#8220;{}&#8220;][et_pb_row _builder_version=&#8220;4.19.4&#8243; 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custom_padding=&#8220;0px||0px||false|false&#8220; global_colors_info=&#8220;{}&#8220;][et_pb_column type=&#8220;4_4&#8243; _builder_version=&#8220;4.19.4&#8243; _module_preset=&#8220;default&#8220; global_colors_info=&#8220;{}&#8220;][et_pb_post_title title=&#8220;off&#8220; author=&#8220;off&#8220; date=&#8220;off&#8220; comments=&#8220;off&#8220; featured_image=&#8220;off&#8220; module_id=&#8220;meta-new&#8220; _builder_version=&#8220;4.19.4&#8243; _module_preset=&#8220;default&#8220; title_font=&#8220;Avant Regular||||||||&#8220; title_text_color=&#8220;#000000&#8243; title_font_size=&#8220;64px&#8220; title_line_height=&#8220;70px&#8220; meta_font=&#8220;Calibri Regular||||||||&#8220; meta_text_color=&#8220;RGBA(255,255,255,0)&#8220; meta_font_size=&#8220;10px&#8220; meta_line_height=&#8220;16px&#8220; custom_margin=&#8220;0px||0px||false|false&#8220; custom_padding=&#8220;0px||20px||false|false&#8220; custom_css_post_meta=&#8220;text-transform: uppercase;&#8220; global_colors_info=&#8220;{}&#8220;][\/et_pb_post_title][et_pb_post_title author=&#8220;off&#8220; date_format=&#8220;j \u00b7 M \u00b7 Y&#8220; comments=&#8220;off&#8220; featured_image=&#8220;off&#8220; _builder_version=&#8220;4.27.3&#8243; _module_preset=&#8220;default&#8220; title_font=&#8220;Avant Regular||||||||&#8220; title_text_color=&#8220;#000000&#8243; title_font_size=&#8220;64px&#8220; title_line_height=&#8220;70px&#8220; meta_font=&#8220;Avant Regular||||||||&#8220; meta_text_color=&#8220;#000000&#8243; meta_font_size=&#8220;14px&#8220; meta_line_height=&#8220;24px&#8220; custom_margin=&#8220;0px||0px||false|false&#8220; custom_padding=&#8220;0px||16px||false|false&#8220; title_font_size_tablet=&#8220;&#8220; title_font_size_phone=&#8220;42px&#8220; title_font_size_last_edited=&#8220;on|phone&#8220; title_line_height_tablet=&#8220;&#8220; title_line_height_phone=&#8220;48px&#8220; title_line_height_last_edited=&#8220;on|phone&#8220; custom_css_post_meta=&#8220;text-transform: uppercase;&#8220; global_colors_info=&#8220;{}&#8220;][\/et_pb_post_title][et_pb_text _builder_version=&#8220;4.27.4&#8243; _module_preset=&#8220;default&#8220; text_font=&#8220;Avant Regular||||||||&#8220; text_text_color=&#8220;#000000&#8243; text_font_size=&#8220;20px&#8220; text_line_height=&#8220;24px&#8220; link_text_color=&#8220;#89BBE5&#8243; custom_margin=&#8220;0px||0px||false|false&#8220; custom_padding=&#8220;0px||0px||false|false&#8220; global_colors_info=&#8220;{}&#8220;]<\/p>\n<p><span>Erforschung von mikrobiellen Metaboliten und Immunaktivierung<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8220;1_2,1_2&#8243; module_id=&#8220;post-content&#8220; _builder_version=&#8220;4.27.3&#8243; _module_preset=&#8220;default&#8220; min_height=&#8220;589px&#8220; custom_margin=&#8220;30px||0px||false|false&#8220; custom_padding=&#8220;0px||0px||false|false&#8220; global_colors_info=&#8220;{}&#8220;][et_pb_column type=&#8220;1_2&#8243; _builder_version=&#8220;4.19.4&#8243; _module_preset=&#8220;default&#8220; custom_padding=&#8220;||0px||false|false&#8220; global_colors_info=&#8220;{}&#8220;][et_pb_text _builder_version=&#8220;4.27.4&#8243; _module_preset=&#8220;default&#8220; text_font=&#8220;Avant Regular||||||||&#8220; text_text_color=&#8220;#000000&#8243; text_font_size=&#8220;30px&#8220; text_line_height=&#8220;36px&#8220; link_font=&#8220;||||on|||#89BBE5|&#8220; link_text_color=&#8220;#89BBE5&#8243; custom_margin=&#8220;0px||0px||false|false&#8220; custom_padding=&#8220;0px||16px||false|false&#8220; global_colors_info=&#8220;{}&#8220;]<\/p>\n<p><span>Entschl\u00fcsselung der Rolle bakterieller Metaboliten bei der Funktion dendritischer Zellen<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text ul_item_indent=&#8220;20px&#8220; ol_item_indent=&#8220;20px&#8220; module_id=&#8220;post-body&#8220; _builder_version=&#8220;4.27.4&#8243; _module_preset=&#8220;default&#8220; text_font=&#8220;Calibri Regular||||||||&#8220; text_text_color=&#8220;#505358&#8243; text_font_size=&#8220;18px&#8220; text_line_height=&#8220;24px&#8220; link_font=&#8220;||||on|||#89BBE5|&#8220; link_text_color=&#8220;#89BBE5&#8243; min_height=&#8220;67px&#8220; custom_margin=&#8220;0px||80px||false|false&#8220; custom_margin_tablet=&#8220;0px||80px||false|false&#8220; custom_margin_phone=&#8220;||48px||false|false&#8220; custom_margin_last_edited=&#8220;on|phone&#8220; custom_padding=&#8220;0px||0px||false|false&#8220; global_colors_info=&#8220;{}&#8220;]<\/p>\n<p><span>Die menschliche Darmmikrobiota, eine komplexe und dynamische Gemeinschaft von Mikroorganismen, die in unserem Verdauungstrakt lebt, spielt eine entscheidende Rolle f\u00fcr Gesundheit und Krankheit. Neue Forschungsergebnisse zeigen ein faszinierendes Zusammenspiel zwischen der Darmmikrobiota, dem Immunsystem und dem Stoffwechsel. Das Darmmikrobiom steht in einem st\u00e4ndigen Dialog mit den Immunzellen, erzieht und reguliert sie, was wiederum die Gesundheit des Darms aufrechterh\u00e4lt und vor Krankheitserregern sch\u00fctzt. Dieses Projekt zielt darauf ab, die verborgenen Mechanismen zu entschl\u00fcsseln, die den Wechselwirkungen zwischen bakteriellen Metaboliten in der Mikroumgebung und der Aktivierung von Immunzellen zugrunde liegen, wobei wir uns insbesondere auf die Auswirkungen bakterieller Metaboliten auf den Stoffwechsel und die biologische Funktion dendritischer Zellen konzentrieren. Vorl\u00e4ufige Daten zeigten, dass bakterielle Metaboliten in hohem Ma\u00dfe von logarithmisch expandierenden Bakterien produziert werden und von DCs wahrgenommen werden k\u00f6nnen, was deren Aktivierung f\u00f6rdert. Es m\u00fcssen noch viele Fragen beantwortet werden&#8230;     <\/span><\/p>\n<p><b>Projektteam:<\/b><span style=\"font-weight: 400;\"> Andrea Celoria<br \/><strong>Finanzierung: <\/strong>SNF<\/span><a href=\"https:\/\/qumea.com\/\"><\/a><span style=\"font-weight: 400;\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8220;1_2&#8243; _builder_version=&#8220;4.19.4&#8243; _module_preset=&#8220;default&#8220; custom_padding=&#8220;||0px||false|false&#8220; global_colors_info=&#8220;{}&#8220;][et_pb_image src=&#8220;https:\/\/www.dcberne.com\/wp-content\/uploads\/2025\/01\/PastedGraphic-1.png&#8220; title_text=&#8220;Eingef\u00fcgteGrafik-1&#8243; _builder_version=&#8220;4.27.4&#8243; _module_preset=&#8220;default&#8220; global_colors_info=&#8220;{}&#8220;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8220;1&#8243; _builder_version=&#8220;4.19.4&#8243; _module_preset=&#8220;default&#8220; background_color=&#8220;#FAFAFA&#8220; 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custom_padding_tablet=&#8220;0px||40px||false|false&#8220; custom_padding_phone=&#8220;||16px||false|false&#8220; custom_padding_last_edited=&#8220;on|phone&#8220; global_colors_info=&#8220;{}&#8220;]<\/p>\n<p>Projekte<\/p>\n<p>[\/et_pb_text][et_pb_blog fullwidth=&#8220;off&#8220; post_type=&#8220;project&#8220; posts_number=&#8220;3&#8243; meta_date=&#8220;j \u00b7 M \u00b7 Y&#8220; excerpt_length=&#8220;120&#8243; show_author=&#8220;off&#8220; show_pagination=&#8220;off&#8220; masonry_tile_background_color=&#8220;RGBA(255,255,255,0)&#8220; module_class=&#8220;dcb-news&#8220; _builder_version=&#8220;4.19.4&#8243; _module_preset=&#8220;default&#8220; header_font=&#8220;Avant Regular||||||||&#8220; header_text_color=&#8220;#000000&#8243; header_font_size=&#8220;20px&#8220; header_line_height=&#8220;24px&#8220; body_font=&#8220;Calibri Regular||||||||&#8220; body_text_color=&#8220;#505358&#8243; body_font_size=&#8220;16px&#8220; body_line_height=&#8220;22px&#8220; meta_font=&#8220;Calibri Regular||||||||&#8220; 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Neue Forschungsergebnisse zeigen ein faszinierendes Zusammenspiel zwischen der Darmmikrobiota, dem Immunsystem und dem Stoffwechsel. Das Darmmikrobiom steht in [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":10242,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"give_campaign_id":0,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[73,72,75,64],"project_tag":[],"class_list":["post-9869","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-ernahrung-stoffwechsel","project_category-forschungsprojekte","project_category-klinische-studie","project_category-technologieprojekte"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bakterielle Metaboliten modulieren die Immunfunktion - Diabetes Center Berne<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.dcberne.com\/de\/project\/hypoxanthin-projekt\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bakterielle Metaboliten modulieren die Immunfunktion - Diabetes Center Berne\" \/>\n<meta property=\"og:description\" content=\"Erforschung von mikrobiellen Metaboliten und ImmunaktivierungEntschl\u00fcsselung der Rolle bakterieller Metaboliten bei der Funktion dendritischer ZellenDie menschliche Darmmikrobiota, eine komplexe und dynamische Gemeinschaft von Mikroorganismen, die in unserem Verdauungstrakt lebt, spielt eine entscheidende Rolle f\u00fcr Gesundheit und Krankheit. Neue Forschungsergebnisse zeigen ein faszinierendes Zusammenspiel zwischen der Darmmikrobiota, dem Immunsystem und dem Stoffwechsel. 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